Coach Kyle Shanahan said Trey Lance suffered a sprained knee in the Week 5 loss to the Cardinals.
The good news is the 49ers have a bye this upcoming week, and Jimmy Garoppolo (calf) wasn't expected to be dealing with a long-term injury prior to being ruled out last week, allowing Lance to get the start. Lance played really poorly, especially as a passer, against Arizona. It would be a surprise if Garoppolo doesn't get his starting job back when healthy. San Francisco has two weeks to figure it out.
SOURCE: Matt Barrows on Twitter Oct 11, 2021, 6:51 PM ET